To improve the lives of individuals with Fanconi anemia through research that focuses on the rapid discovery and development of therapies or strategies that treat, control, or cure Fanconi anemia. Particular interest in supporting interdisciplinary and translational research efforts that effectively address one or more of the following priorities: 1. To understand how alteration of the Fanconi anemia genes and their products lead to the clinical manifestations of Fanconi anemia.
2. To determine the causes of bone marrow failure, myelodysplasia and leukemia in individuals with Fanconi anemia, and to develop strategies to prevent, treat, and cure these disorders.
3. To define the pathogenesis of Fanconi anemia-associated cancers, and to develop strategies for prevention, early detection, treatment and cure.
4. To identify practical and proactive management strategies that families and persons with Fanconi anemia can use to maintain a high quality of life.
5.To support the creation of shared resources, databases, and technologies for the international Fanconi anemia research community.