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The 2020 Michelson Prizes will focus on Human Immunology, Vaccine Discovery and Immunotherapy Research. The selection committee will be looking to support research that is both highly innovative and has the potential for high impact. Specifically, projects should propose innovative ideas and approaches that can be applied across many disease areas and states. Projects should have the potential to significantly expand our understanding of the human immune system and accelerate the development of vaccines and immunotherapies.