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This award mechanism is appropriate for clinical (i.e. M.D.) fellows/faculty proposing clinical, patient-oriented research projects that involve direct interactions with human subjects/patients. This includes studies such as therapeutic interventions or clinical trials. Komen defines clinical research as hypothesis driven, patient-oriented research for which an investigator directly interacts with human subjects/patients, in conjunction with laboratory-based research, as appropriate. This includes studies such as therapeutic interventions or clinical trials.